What is BPC-157? Research overview

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids. It is a partial sequence of a larger protein found in gastric juice. Its CAS number is 137525-51-0.

BPC-157 is classified as a research-use-only (RUO) compound and is not approved for human therapeutic use. All research using this compound must comply with applicable regulations.

In vitro and animal model research suggests BPC-157 may interact with several biological pathways:

• Growth hormone receptor pathways — BPC-157 has been studied for its potential modulation of the GH-receptor signalling cascade, which is implicated in cellular growth and repair.

• Nitric oxide (NO) system — Several studies have demonstrated an effect on NO production, which plays a role in vascular function and tissue perfusion.

• Tendon and ligament fibroblasts — Research in rat models has shown accelerated collagen reorganisation following tendon injury.

• Gastrointestinal mucosa — Originally derived from gastric juice, studies have investigated its cytoprotective effects on the intestinal epithelium.

The majority of published research uses rodent models (rat or mouse). Key areas of investigation include:

• . Tendon-to-bone healing (Achilles tendon transection models)
• . Muscle repair after crush injury
• . Intestinal anastomosis healing
• . Corneal wound healing
• . Bone regeneration in fracture models

As of 2026, no double-blind placebo-controlled human clinical trials have been completed or published.

BPC-157 is supplied as a lyophilized (freeze-dried) powder. For laboratory use:

• Store at −20 °C (long-term) or 4 °C (short-term, ≤ 4 weeks)
• Reconstitute with bacteriostatic water (0.9% benzyl alcohol) or sterile saline
• Avoid repeated freeze-thaw cycles
• Protect from light and moisture

BioSyncLabs BPC-157 is independently verified to ≥ 99% purity by reverse-phase HPLC. A Certificate of Analysis (CoA) is supplied with every order. The CoA includes the HPLC chromatogram, mass spectrometry confirmation, and lot number.