
For Research Use Only
All products are intended strictly for laboratory research purposes only.
See the Certificate of Analysis for this batch
Independent HPLC purity report. Every batch traceable to the lab that signed it off.
Purity
≥ 99%
Method
HPLC
Tested
April 2026
We accept
CJC-1295 (No DAC) is a synthetic 29-amino acid analogue of endogenous growth hormone-releasing hormone (GHRH 1-29), engineered with targeted amino acid substitutions to improve receptor binding affinity and resistance to enzymatic degradation while preserving natural GH pulsatility. Supplied as a lyophilized powder in a sealed pharmaceutical-grade glass vial. Intended for in-vitro and laboratory research applications only.
Mechanism of Action
CJC-1295 (No DAC) acts as a selective agonist at the growth hormone-releasing hormone receptor (GHRHR) on somatotroph cells of the anterior pituitary, stimulating pulsatile growth hormone secretion in a physiologically mirrored pattern. Its amino acid substitutions at positions 2, 8, 15, and 27 confer enhanced stability against dipeptidyl peptidase-IV (DPP-IV) cleavage and plasma proteases compared to native GHRH, while the absence of the Drug Affinity Complex (DAC) results in a shorter half-life that preserves natural GH pulse architecture. This profile makes it a subject of interest in growth hormone axis research, metabolic studies, and somatotropic function investigation.
Specifications
• Sequence: Validated by mass spectrometry (MS/MS)
• Purity: ≥ 98% by HPLC
• Form: Lyophilized powder
• Molecular Weight: 3,367.9 Da
• Storage: 2 – 8 °C, keep dry and away from light
• Shelf Life: 24 months from manufacture date (sealed)
Quality & Testing
Every batch is independently tested by a certified third-party laboratory. A Certificate of Analysis (CoA) confirming purity and identity is available for each batch.
CJC-1295 (No DAC)· 5mg
5mg
€39.90
€49.99