| Purity | > 99% |
| Form | Lyophilized Powder |
| Milligram | 5mg |
| Purity | > 99% |
| Form | Lyophilized Powder |
| Milligram | 5mg |
❌ For Research Use Only
For laboratory research only. Not for human consumption.
CJC-1295 (No DAC) is a synthetic 29-amino acid analogue of endogenous growth hormone-releasing hormone (GHRH 1-29), engineered with targeted amino acid substitutions to improve receptor binding affinity and resistance to enzymatic degradation while preserving natural GH pulsatility. Supplied as a lyophilized powder in a sealed pharmaceutical-grade glass vial. Intended for in-vitro and laboratory research applications only.
Mechanism of Action
CJC-1295 (No DAC) acts as a selective agonist at the growth hormone-releasing hormone receptor (GHRHR) on somatotroph cells of the anterior pituitary, stimulating pulsatile growth hormone secretion in a physiologically mirrored pattern. Its amino acid substitutions at positions 2, 8, 15, and 27 confer enhanced stability against dipeptidyl peptidase-IV (DPP-IV) cleavage and plasma proteases compared to native GHRH, while the absence of the Drug Affinity Complex (DAC) results in a shorter half-life that preserves natural GH pulse architecture. This profile makes it a subject of interest in growth hormone axis research, metabolic studies, and somatotropic function investigation.
Specifications
• Sequence: Validated by mass spectrometry (MS/MS)
• Purity: ≥ 98% by HPLC
• Form: Lyophilized powder
• Molecular Weight: 3,367.9 Da
• Storage: 2 – 8 °C, keep dry and away from light
• Shelf Life: 24 months from manufacture date (sealed)
Quality & Testing
Every batch is independently tested by a certified third-party laboratory. A Certificate of Analysis (CoA) confirming purity and identity is available for each batch.
CJC-1295 (No DAC)
€45.90
